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Objective To observe the effect of low-dose remifentanil combined with propofol on the blood pressure(BP),heart rate(HR)and neonatal Apgar score in parturients undergoing cesarean section. Methods Forty-two parturients undergoing cesarean section were placed in two groups:low-dose remifentanil combined with propofol general anesthesia group(group GA,n=20)and neuraxial anesthesia group(group RA, n=22).BP and HR at the basis line(T0),pre-incision(T1),instant incision(T2),1 min(T3),3 min(T4),5 min(T5)after incision,cutting the umbilical cord(T6)were recorded,and neonatal Apgar scores at 1 min and 5 min after birth were also recorded. Results In group GA,the systolic blood pressure(SBP)and the diastolic blood pressure(DBP)remained unchanged at any time(P > 0.05). Compared with T0,HRs at T1~ T4were de-creased significantly(P<0.05).In group RA,compared with T0,the levels of SBP,DBP,HR at T1~T4were de-creased significantly(P<0.05).The levels of SBP and DBP at T1~T4in group GA were significantly higher than those in group RA(P<0.05),but there was no significant difference in HR between the two groups(P>0.05). The number of cases of ephedrine in group RA was significantly larger than that in the group GA(P<0.05).Neo-natal Apgar scores at 1 min and 5 min after birth were similar between the two groups(P > 0.05). Conclusion The application of low-doseremifentanil and propofol can be safely used in cesarean section,for the stability of par-turient BP and HR and no risk of neonatal respiratory depression.
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Objective To investigate the influence of the different second stage of labor duration on the maternal and neo‐natal outcomes .Methods Data were retrospectively analyzed from 201 nulliparous women delivering a singleton infant in cephalic presentation without labor analgesia hospitalized in our hospital between January 2012 and May 2015 ,whose second stage pro‐gressed beyond 2 hours .They were divided into observation group and control group according to different second stage of labor du‐ration ,and cases with a second stage of labor duration of three hours were in the observation group (163 cases) ,and those within two hours were in the control group (38 cases) .Results Whether the limit of the second stage of labor duration of 2 hours ,or 3 hours ,the risk of postpartum hemorrhage ,postpartum fever ,urinary retention and neonatal asphyxia ,admission to the neonatology department in two groups were not significantly different(P>0 .05) .However ,there was significance difference in the rate of soft birth canal laceration(72 cases in the observation group) ,poor wound healing (0 case in the observation group and 3 cases in the control group ,P<0 .05) .Conclusion a second stage of labor duration of 3 hours could reduce the rate of cesarean section ,and with no increase in severe adverse maternal and neonatal outcomes .
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OBJECTIVE:To observe the application of sevoflurane combined with different dose of fentanyl in general anesthesia-inducing endotracheal intubation in adults. METHODS:60 selective patients were randomly divided into three groups(n=20). In haled 8% sevoflurane inductal anesthesia with tidal volume method. When the patients breathing and his own,and loss of eyelvaisah i .rve.f lTehxe, SgBroPu,p DⅠBwP earne dg iHvRen in2 e?agc?hk ggr-o1 ufpe nwtaenrye l dveitae cit.evd., agt rtoimupe Ⅱof 3lo s?sg-? okf-g -ey1 efleanstha nryelf lvexia ain.vd. baenfdo rger oinudpu Ⅲcti o4n ?agn?esktgh-e1s ifae(ntTan0)y,l before intubation(T1),at the moment of intubation(T2),at 1 min after intubation(T3),3 min after intubation(T4),5 min after intubation(T5)and 10 min after intubation(T6). RESULTS:Compared with at T0,SBP,DBP and HR in three groups were significantly decreased at T1(P0.05). SBP, fDeBntPa naynld i sH eRff einc tigvreo utop iⅢnd uwceer ea ndeescthreeassiae di nm aadrukletd elyn daot trTa(2chPe
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0.05).CONCLUSION:Neuromuscular blockade induced by single i.v.of Cisatracurium showed no gender difference.